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Mechanisms of autophagy activation in endothelial cell and their targeting during normothermic machine liver perfusion

Ischaemia-reperfusion injury (IRI) is the leading cause of injury seen in the liver following transplantation. IRI also causes injury following liver surgery and haemodynamic shock. The first cells within the liver to be injured by IRI are the liver sinusoidal endothelial cells (LSEC). Recent eviden...

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Detalles Bibliográficos
Autores principales: Boteon, Yuri L, Laing, Richard, Mergental, Hynek, Reynolds, Gary M, Mirza, Darius F, Afford, Simon C, Bhogal, Ricky H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752706/
https://www.ncbi.nlm.nih.gov/pubmed/29358854
http://dx.doi.org/10.3748/wjg.v23.i48.8443