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Partitioning Phenotypic Variance Due to Parent-of-Origin Effects Using Genomic Relatedness Matrices
We propose a new method, G-REMLadp, to estimate the phenotypic variance explained by parent-of-origin effects (POEs) across the genome. Our method uses restricted maximum likelihood analysis of genome-wide genetic relatedness matrices based on individuals’ phased genotypes. Genome-wide SNP data from...
Autores principales: | Laurin, Charles, Cuellar-Partida, Gabriel, Hemani, Gibran, Smith, George Davey, Yang, Jian, Evans, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752821/ https://www.ncbi.nlm.nih.gov/pubmed/29098496 http://dx.doi.org/10.1007/s10519-017-9880-0 |
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