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Derivation of hypermethylated pluripotent embryonic stem cells with high potency

Naive hypomethylated embryonic pluripotent stem cells (ESCs) are developmentally closest to the preimplantation epiblast of blastocysts, with the potential to contribute to all embryonic tissues and the germline, excepting the extra-embryonic tissues in chimeric embryos. By contrast, epiblast stem c...

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Detalles Bibliográficos
Autores principales: Bao, Siqin, Tang, Walfred WC, Wu, Baojiang, Kim, Shinseog, Li, Jingyun, Li, Lin, Kobayashi, Toshihiro, Lee, Caroline, Chen, Yanglin, Wei, Mengyi, Li, Shudong, Dietmann, Sabine, Tang, Fuchou, Li, Xihe, Surani, M Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752839/
https://www.ncbi.nlm.nih.gov/pubmed/29076502
http://dx.doi.org/10.1038/cr.2017.134