WH2 and proline‐rich domains of WASP‐family proteins collaborate to accelerate actin filament elongation

WASP‐family proteins are known to promote assembly of branched actin networks by stimulating the filament‐nucleating activity of the Arp2/3 complex. Here, we show that WASP‐family proteins also function as polymerases that accelerate elongation of uncapped actin filaments. When clustered on a surfac...

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Detalles Bibliográficos
Autores principales: Bieling, Peter, Hansen, Scott D, Akin, Orkun, Li, Tai‐De, Hayden, Carl C, Fletcher, Daniel A, Mullins, R Dyche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753033/
https://www.ncbi.nlm.nih.gov/pubmed/29141912
http://dx.doi.org/10.15252/embj.201797039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753033/
https://www.ncbi.nlm.nih.gov/pubmed/29141912
http://dx.doi.org/10.15252/embj.201797039

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