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The synthesis of the 2,3-difluorobutan-1,4-diol diastereomers

The diastereoselective synthesis of fluorinated building blocks that contain chiral fluorine substituents is of interest. Here we describe optimisation efforts in the synthesis of anti-2,3-difluorobutane-1,4-diol, as well as the synthesis of the corresponding syn-diastereomer. Both targets were synt...

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Detalles Bibliográficos
Autores principales: Szpera, Robert, Kovalenko, Nadia, Natarajan, Kalaiselvi, Paillard, Nina, Linclau, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753060/
https://www.ncbi.nlm.nih.gov/pubmed/30018668
http://dx.doi.org/10.3762/bjoc.13.280