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The synthesis of the 2,3-difluorobutan-1,4-diol diastereomers
The diastereoselective synthesis of fluorinated building blocks that contain chiral fluorine substituents is of interest. Here we describe optimisation efforts in the synthesis of anti-2,3-difluorobutane-1,4-diol, as well as the synthesis of the corresponding syn-diastereomer. Both targets were synt...
Autores principales: | Szpera, Robert, Kovalenko, Nadia, Natarajan, Kalaiselvi, Paillard, Nina, Linclau, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753060/ https://www.ncbi.nlm.nih.gov/pubmed/30018668 http://dx.doi.org/10.3762/bjoc.13.280 |
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