Preliminary Evidence for Aortopathy and an X-Linked Parent-of-Origin Effect on Aortic Valve Malformation in a Mouse Model of Turner Syndrome

Turner syndrome (TS), most frequently caused by X-monosomy (45,X), is characterized in part by cardiovascular abnormalities, including aortopathy and bicuspid aortic valve (BAV). There is a need for animal models that recapitulate the cardiovascular manifestations of TS. Extracellular matrix (ECM) o...

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Detalles Bibliográficos
Autores principales: Hinton, Robert B., Opoka, Amy M., Ojarikre, Obah A., Wilkinson, Lawrence S., Davies, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753145/
https://www.ncbi.nlm.nih.gov/pubmed/29371518
http://dx.doi.org/10.3390/jcdd2030190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753145/
https://www.ncbi.nlm.nih.gov/pubmed/29371518
http://dx.doi.org/10.3390/jcdd2030190

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