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Recent progress in the racemic and enantioselective synthesis of monofluoroalkene-based dipeptide isosteres

Monofluoroalkenes are fluorinated motifs that can be used to replace amide bonds. In order to be incorporated into peptides, it is normally necessary to first synthesize a dipeptide where the amide bond has been replaced with a monofluoroalkene. In that context, this review will present the racemic...

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Detalles Bibliográficos
Autores principales: Drouin, Myriam, Paquin, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753175/
https://www.ncbi.nlm.nih.gov/pubmed/29564002
http://dx.doi.org/10.3762/bjoc.13.262