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GPCRdb in 2018: adding GPCR structure models and ligands

G protein-coupled receptors are the most abundant mediators of both human signalling processes and therapeutic effects. Herein, we report GPCRome-wide homology models of unprecedented quality, and roughly 150 000 GPCR ligands with data on biological activities and commercial availability. Based on t...

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Detalles Bibliográficos
Autores principales: Pándy-Szekeres, Gáspár, Munk, Christian, Tsonkov, Tsonko M, Mordalski, Stefan, Harpsøe, Kasper, Hauser, Alexander S, Bojarski, Andrzej J, Gloriam, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753179/
https://www.ncbi.nlm.nih.gov/pubmed/29155946
http://dx.doi.org/10.1093/nar/gkx1109