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PICKLES: the database of pooled in-vitro CRISPR knockout library essentiality screens

The adaptation of CRISPR/Cas9 systems for pooled library genetic knockout screens in mammalian cells has substantially advanced the state of the art in human functional genomics. Screening panels of cell lines for genes whose knockout imposes a significant fitness defect has dramatically expanded ou...

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Detalles Bibliográficos
Autores principales: Lenoir, Walter F, Lim, Tassica L, Hart, Traver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753353/
https://www.ncbi.nlm.nih.gov/pubmed/29077937
http://dx.doi.org/10.1093/nar/gkx993