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DiseaseEnhancer: a resource of human disease-associated enhancer catalog

Large-scale sequencing studies discovered substantial genetic variants occurring in enhancers which regulate genes via long range chromatin interactions. Importantly, such variants could affect enhancer regulation by changing transcription factor bindings or enhancer hijacking, and in turn, make an...

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Detalles Bibliográficos
Autores principales: Zhang, Guanxiong, Shi, Jian, Zhu, Shiwei, Lan, Yujia, Xu, Liwen, Yuan, Huating, Liao, Gaoming, Liu, Xiaoqin, Zhang, Yunpeng, Xiao, Yun, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753380/
https://www.ncbi.nlm.nih.gov/pubmed/29059320
http://dx.doi.org/10.1093/nar/gkx920