Brainstem tau pathology in Alzheimer’s disease is characterized by increase of three repeat tau and independent of amyloid β

INTRODUCTION: Alzheimer-type neuropil threads (NTs) and neurofibrillary tangles (NFTs) are comprised of either 4 repeat (4R)-tau, 3 repeat (3R)-tau, or a mixture of both. In the hippocampus, the number of NFTs, and the proportion of 3R tau progressively increases. If this preferential accumulation o...

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Detalles Bibliográficos
Autores principales: Uematsu, Miho, Nakamura, Ayako, Ebashi, Momoko, Hirokawa, Katsuiku, Takahashi, Ryosuke, Uchihara, Toshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753447/
https://www.ncbi.nlm.nih.gov/pubmed/29298724
http://dx.doi.org/10.1186/s40478-017-0501-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753447/
https://www.ncbi.nlm.nih.gov/pubmed/29298724
http://dx.doi.org/10.1186/s40478-017-0501-1

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