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Global accumulation of circRNAs during aging in Caenorhabditis elegans

BACKGROUND: Circular RNAs (CircRNAs) are a newly appreciated class of RNAs that lack free 5′ and 3′ ends, are expressed by the thousands in diverse forms of life, and are mostly of enigmatic function. Ostensibly due to their resistance to exonucleases, circRNAs are known to be exceptionally stable....

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Detalles Bibliográficos
Autores principales: Cortés-López, Mariela, Gruner, Matthew R., Cooper, Daphne A., Gruner, Hannah N., Voda, Alexandru-Ioan, van der Linden, Alexander M., Miura, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753478/
https://www.ncbi.nlm.nih.gov/pubmed/29298683
http://dx.doi.org/10.1186/s12864-017-4386-y