Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells

BACKGROUND: Long Interspersed Nuclear Element-1 (LINE-1) is an autonomous retrotransposon that generates new genomic insertions through the retrotransposition of a RNA intermediate. Expression of LINE-1 is tightly repressed in most somatic tissues to prevent DNA damage and ensure genomic integrity....

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Detalles Bibliográficos
Autores principales: Briggs, Erica M., Ha, Susan, Mita, Paolo, Brittingham, Gregory, Sciamanna, Ilaria, Spadafora, Corrado, Logan, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753491/
https://www.ncbi.nlm.nih.gov/pubmed/29308092
http://dx.doi.org/10.1186/s13100-017-0106-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753491/
https://www.ncbi.nlm.nih.gov/pubmed/29308092
http://dx.doi.org/10.1186/s13100-017-0106-z

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