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Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy: translational implications for interventional therapies

Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder characterized by widespread oligodendroglial cytoplasmic inclusions of filamentous α-synuclein, and neuronal loss in autonomic centres, basal ganglia and cerebellar circuits. It has been suggested that primary oligoden...

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Detalles Bibliográficos
Autores principales: Refolo, Violetta, Bez, Francesco, Polissidis, Alexia, Kuzdas-Wood, Daniela, Sturm, Edith, Kamaratou, Martina, Poewe, Werner, Stefanis, Leonidas, Angela Cenci, M., Romero-Ramos, Marina, Wenning, Gregor K., Stefanova, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753576/
https://www.ncbi.nlm.nih.gov/pubmed/29298733
http://dx.doi.org/10.1186/s40478-017-0504-y