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Cell-specific prediction and application of drug-induced gene expression profiles

Gene expression profiling of in vitro drug perturbations is useful for many biomedical discovery applications including drug repurposing and elucidation of drug mechanisms. However, limited data availability across cell types has hindered our capacity to leverage or explore the cell-specificity of t...

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Detalles Bibliográficos
Autores principales: Hodos, Rachel, Zhang, Ping, Lee, Hao-Chih, Duan, Qiaonan, Wang, Zichen, Clark, Neil R., Ma'ayan, Avi, Wang, Fei, Kidd, Brian, Hu, Jianying, Sontag, David, Dudley, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753597/
https://www.ncbi.nlm.nih.gov/pubmed/29218867