Evaluation of Polyamine Transport Inhibitors in a Drosophila Epithelial Model Suggests the Existence of Multiple Transport Systems

Increased polyamine biosynthesis activity and an active polyamine transport system are characteristics of many cancer cell lines and polyamine depletion has been shown to be a viable anticancer strategy. Polyamine levels can be depleted by difluoromethylornithine (DFMO), an inhibitor of the key poly...

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Detalles Bibliográficos
Autores principales: Wang, Minpei, Phanstiel, Otto, von Kalm, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753656/
https://www.ncbi.nlm.nih.gov/pubmed/29135915
http://dx.doi.org/10.3390/medsci5040027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753656/
https://www.ncbi.nlm.nih.gov/pubmed/29135915
http://dx.doi.org/10.3390/medsci5040027

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