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Helicobacter pylori Is Associated with miR-133a Expression through Promoter Methylation in Gastric Carcinogenesis

BACKGROUND/AIMS: To investigate whether Helicobacter pylori eradication can reverse epigenetic silencing of microRNAs (miRNAs) which are associated with H. pylori-induced gastric carcinogenesis. METHODS: We examined expression and promoter methylation of miR-34b/c, miR-133a, let-7a, and let-7i in ga...

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Detalles Bibliográficos
Autores principales: Lim, Joo Hyun, Kim, Sang Gyun, Choi, Ji Min, Yang, Hyo-Joon, Kim, Joo Sung, Jung, Hyun Chae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of Gut and Liver 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753685/
https://www.ncbi.nlm.nih.gov/pubmed/28950691
http://dx.doi.org/10.5009/gnl17263