Stringent Nucleotide Recognition by the Ribosome at the Middle Codon Position

Accurate translation of the genetic code depends on mRNA:tRNA codon:anticodon base pairing. Here we exploit an emissive, isosteric adenosine surrogate that allows direct measurement of the kinetics of codon:anticodon base formation during protein synthesis. Our results suggest that codon:anticodon b...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Shin, Dongwon, Ng, Martin, Sanbonmatsu, Karissa Y., Tor, Yitzhak, Cooperman, Barry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753802/
https://www.ncbi.nlm.nih.gov/pubmed/28850078
http://dx.doi.org/10.3390/molecules22091427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753802/
https://www.ncbi.nlm.nih.gov/pubmed/28850078
http://dx.doi.org/10.3390/molecules22091427

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