Blocking the VISTA pathway enhances disease progression in (NZB × NZW) F1 female mice

V-domain Ig suppressor of T-cell activation (VISTA) is a critical negative checkpoint molecule involved in regulating the immune response. Targeting the pathway with an antagonist anti-VISTA antibody designated 13F3 has been shown to enhance disease severity in experimental autoimmune encephalomyeli...

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Detalles Bibliográficos
Autores principales: Sergent, PA, Plummer, SF, Pettus, J, Mabaera, R, DeLong, JK, Pechenick, DA, Burns, CM, Noelle, RJ, Ceeraz, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753845/
https://www.ncbi.nlm.nih.gov/pubmed/28659048
http://dx.doi.org/10.1177/0961203317716322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753845/
https://www.ncbi.nlm.nih.gov/pubmed/28659048
http://dx.doi.org/10.1177/0961203317716322

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