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The Evolution of Gene-Specific Transcriptional Noise Is Driven by Selection at the Pathway Level
Biochemical reactions within individual cells result from the interactions of molecules, typically in small numbers. Consequently, the inherent stochasticity of binding and diffusion processes generates noise along the cascade that leads to the synthesis of a protein from its encoding gene. As a res...
Autores principales: | Barroso, Gustavo Valadares, Puzovic, Natasa, Dutheil, Julien Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753856/ https://www.ncbi.nlm.nih.gov/pubmed/29097405 http://dx.doi.org/10.1534/genetics.117.300467 |
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