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Using Separation-of-Function Mutagenesis To Define the Full Spectrum of Activities Performed by the Est1 Telomerase Subunit in Vivo

A leading objective in biology is to identify the complete set of activities that each gene performs in vivo. In this study, we have asked whether a genetic approach can provide an efficient means of achieving this goal, through the identification and analysis of a comprehensive set of separation-of...

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Detalles Bibliográficos
Autores principales: Lubin, Johnathan W., Tucey, Timothy M., Lundblad, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753878/
https://www.ncbi.nlm.nih.gov/pubmed/29187507
http://dx.doi.org/10.1534/genetics.117.300145