Systemic delivery of MicroRNA mimics with polyethylenimine elevates pulmonary microRNA levels, but lacks pulmonary selectivity

Reversing pathologic alterations in vascular microRNA (miRNA) expression represents a potential therapeutic strategy for pulmonary hypertension. While polyethylenimine (PEI) has previously been shown to be an effective vehicle for vascular lung-directed delivery of plasmid DNA, it remains unclear wh...

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Detalles Bibliográficos
Autores principales: Schlosser, Kenny, Taha, Mohamad, Deng, Yupu, Stewart, Duncan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753929/
https://www.ncbi.nlm.nih.gov/pubmed/29251557
http://dx.doi.org/10.1177/2045893217750613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753929/
https://www.ncbi.nlm.nih.gov/pubmed/29251557
http://dx.doi.org/10.1177/2045893217750613

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