Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cells

Molecular determinants and mechanisms of arthropod-borne flavivirus transmission to the vertebrate host are poorly understood. In this study, we show for the first time that a cell line from medically important arthropods, such as ticks, secretes extracellular vesicles (EVs) including exosomes that...

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Detalles Bibliográficos
Autores principales: Zhou, Wenshuo, Woodson, Michael, Neupane, Biswas, Bai, Fengwei, Sherman, Michael B., Choi, Kyung H., Neelakanta, Girish, Sultana, Hameeda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754134/
https://www.ncbi.nlm.nih.gov/pubmed/29300779
http://dx.doi.org/10.1371/journal.ppat.1006764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754134/
https://www.ncbi.nlm.nih.gov/pubmed/29300779
http://dx.doi.org/10.1371/journal.ppat.1006764

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