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Analytical profiling of mutations in quinolone resistance determining region of gyrA gene among UPEC

Mutations in gyrA are the primary cause of quinolone resistance encountered in gram-negative clinical isolates. The prospect of this work was to analyze the role of gyrA mutations in eliciting high quinolone resistance in uropathogenic E.coli (UPEC) through molecular docking studies. Quinolone susce...

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Detalles Bibliográficos
Autores principales: Varughese, Lesley R., Rajpoot, Meenakshi, Goyal, Soniya, Mehra, Ravinder, Chhokar, Vinod, Beniwal, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754135/
https://www.ncbi.nlm.nih.gov/pubmed/29300775
http://dx.doi.org/10.1371/journal.pone.0190729