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Myeloid cell recruitment versus local proliferation differentiates susceptibility from resistance to filarial infection

Both T(H)2-dependent helminth killing and suppression of the T(H)2 effector response have been attributed to macrophages (MΦ) activated by IL-4 (M(IL-4)). To investigate how M(IL-4) contribute to diverse infection outcomes, the MΦ compartment of susceptible BALB/c mice and more resistant C57BL/6 mic...

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Detalles Bibliográficos
Autores principales: Campbell, Sharon M, Knipper, Johanna A, Ruckerl, Dominik, Finlay, Conor M, Logan, Nicola, Minutti, Carlos M, Mack, Matthias, Jenkins, Stephen J, Taylor, Matthew D, Allen, Judith E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754202/
https://www.ncbi.nlm.nih.gov/pubmed/29299998
http://dx.doi.org/10.7554/eLife.30947