A MIG-15/JNK-1 MAP kinase cascade opposes RPM-1 signaling in synapse formation and learning

The Pam/Highwire/RPM-1 (PHR) proteins are conserved intracellular signaling hubs that regulate synapse formation and axon termination. The C. elegans PHR protein, called RPM-1, acts as a ubiquitin ligase to inhibit the DLK-1 and MLK-1 MAP kinase pathways. We have identified several kinases that are...

Descripción completa

Detalles Bibliográficos
Autores principales: Crawley, Oliver, Giles, Andrew C., Desbois, Muriel, Kashyap, Sudhanva, Birnbaum, Rayna, Grill, Brock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754208/
https://www.ncbi.nlm.nih.gov/pubmed/29228003
http://dx.doi.org/10.1371/journal.pgen.1007095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754208/
https://www.ncbi.nlm.nih.gov/pubmed/29228003
http://dx.doi.org/10.1371/journal.pgen.1007095

Ejemplares similares