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Vitamin D attenuates sphingosine-1-phosphate (S1P)-mediated inhibition of extravillous trophoblast migration

INTRODUCTION: Failure of trophoblast invasion and remodelling of maternal blood vessels leads to the pregnancy complication pre-eclampsia (PE). In other systems, the sphingolipid, sphingosine-1-phosphate (S1P), controls cell migration therefore this study determined its effect on extravillous tropho...

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Detalles Bibliográficos
Autores principales: Westwood, Melissa, Al-Saghir, Khiria, Finn-Sell, Sarah, Tan, Cherlyn, Cowley, Elizabeth, Berneau, Stéphane, Adlam, Daman, Johnstone, Edward D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754325/
https://www.ncbi.nlm.nih.gov/pubmed/29208234
http://dx.doi.org/10.1016/j.placenta.2017.09.009