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Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype
Blood-brain barrier (BBB) dysfunction might be an important component of many neurodegenerative disorders. In this study, we investigated its role in dementia using large clinical cohorts. The cerebrospinal fluid (CSF)/plasma albumin ratio (Qalb), an indicator of BBB (and blood-CSF barrier) permeabi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754327/ https://www.ncbi.nlm.nih.gov/pubmed/28061383 http://dx.doi.org/10.1016/j.neurobiolaging.2016.11.017 |