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Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype

Blood-brain barrier (BBB) dysfunction might be an important component of many neurodegenerative disorders. In this study, we investigated its role in dementia using large clinical cohorts. The cerebrospinal fluid (CSF)/plasma albumin ratio (Qalb), an indicator of BBB (and blood-CSF barrier) permeabi...

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Detalles Bibliográficos
Autores principales:	Janelidze, Shorena, Hertze, Joakim, Nägga, Katarina, Nilsson, Karin, Nilsson, Christer, Wennström, Malin, van Westen, Danielle, Blennow, Kaj, Zetterberg, Henrik, Hansson, Oskar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754327/ https://www.ncbi.nlm.nih.gov/pubmed/28061383 http://dx.doi.org/10.1016/j.neurobiolaging.2016.11.017

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