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Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging

The influenza A virus genome is composed of eight single-stranded negative-sense RNAs. Eight distinct viral RNA segments (vRNAs) are selectively packaged into progeny virions, with eight vRNAs in ribonucleoprotein complexes (RNPs) arranged in a specific “1+7” pattern, that is, one central RNP surrou...

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Detalles Bibliográficos
Autores principales: Noda, Takeshi, Murakami, Shin, Nakatsu, Sumiho, Imai, Hirotaka, Muramoto, Yukiko, Shindo, Keiko, Sagara, Hiroshi, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754346/
https://www.ncbi.nlm.nih.gov/pubmed/29302061
http://dx.doi.org/10.1038/s41467-017-02517-w