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Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss

Microbial metabolites are known to modulate immune responses of the host. The main metabolites derived from microbial fermentation of dietary fibers in the intestine, short-chain fatty acids (SCFA), affect local and systemic immune functions. Here we show that SCFA are regulators of osteoclast metab...

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Detalles Bibliográficos
Autores principales: Lucas, Sébastien, Omata, Yasunori, Hofmann, Jörg, Böttcher, Martin, Iljazovic, Aida, Sarter, Kerstin, Albrecht, Olivia, Schulz, Oscar, Krishnacoumar, Brenda, Krönke, Gerhard, Herrmann, Martin, Mougiakakos, Dimitrios, Strowig, Till, Schett, Georg, Zaiss, Mario M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754356/
https://www.ncbi.nlm.nih.gov/pubmed/29302038
http://dx.doi.org/10.1038/s41467-017-02490-4