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A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche

Disease recurrence after therapy, due to the persistence of resistant leukemic cells, represents a fundamental problem in the treatment of leukemia. Elucidating the mechanisms responsible for the maintenance of leukemic cells, before and after treatment, is therefore critical to identify curative mo...

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Detalles Bibliográficos
Autores principales: Guarnerio, Jlenia, Mendez, Lourdes Maria, Asada, Noboru, Menon, Archita Venugopal, Fung, Jacqueline, Berry, Kelsey, Frenette, Paul S., Ito, Keisuke, Pandolfi, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754357/
https://www.ncbi.nlm.nih.gov/pubmed/29302031
http://dx.doi.org/10.1038/s41467-017-02427-x