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The earlier, the better: the effects of different administration timepoints of sorafenib in suppressing the carcinogenesis of VEGF in rats

PURPOSE: To investigate the optimal starting time point of sorafenib therapy in suppressing the tumor-promoting effects of VEGF up-regulation, which is frequently found after local therapy in clinical practice. METHODS: VEGF was intravenously injected to imitate the evaluated expression after local...

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Detalles Bibliográficos
Autores principales: Li, Nan, Chen, Bin, Lin, Run, Liu, Ni, Dai, Hai-tao, Tang, Ke-yu, Yang, Jian-yong, Huang, Yong-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754402/
https://www.ncbi.nlm.nih.gov/pubmed/29196964
http://dx.doi.org/10.1007/s00280-017-3493-4