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Dynamic landscape of the local translation at activated synapses

The mammalian target of rapamycin (mTOR) signaling pathway is the central regulator of cap-dependent translation at the synapse. Disturbances in mTOR pathway have been associated with several neurological diseases, such as autism and epilepsy. RNA-binding protein FMRP, a negative regulator of transl...

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Detalles Bibliográficos
Autores principales: Khlebodarova, T M, Kogai, V V, Trifonova, E A, Likhoshvai, V A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754473/
https://www.ncbi.nlm.nih.gov/pubmed/29203851
http://dx.doi.org/10.1038/mp.2017.245