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Dynamic landscape of the local translation at activated synapses
The mammalian target of rapamycin (mTOR) signaling pathway is the central regulator of cap-dependent translation at the synapse. Disturbances in mTOR pathway have been associated with several neurological diseases, such as autism and epilepsy. RNA-binding protein FMRP, a negative regulator of transl...
Autores principales: | Khlebodarova, T M, Kogai, V V, Trifonova, E A, Likhoshvai, V A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754473/ https://www.ncbi.nlm.nih.gov/pubmed/29203851 http://dx.doi.org/10.1038/mp.2017.245 |
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