A Small Molecule Impedes Insulin Fibrillation: Another New Role of Phenothiazine Derivatives

Protein misfolding is interrelated to several diseases, including neurodegenerative diseases and type II diabetes. Misfolded/unfolded proteins produce soluble oligomers that accumulate into “amyloid plaques”. Inhibition of amyloid‐plaque formation by those misfolded/unfolded proteins will lead to th...

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Detalles Bibliográficos
Autores principales: Mukherjee, Meghomukta, Jana, Jagannath, Chatterjee, Subhrangsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754551/
https://www.ncbi.nlm.nih.gov/pubmed/29318099
http://dx.doi.org/10.1002/open.201700131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754551/
https://www.ncbi.nlm.nih.gov/pubmed/29318099
http://dx.doi.org/10.1002/open.201700131

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