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A Small Molecule Impedes Insulin Fibrillation: Another New Role of Phenothiazine Derivatives
Protein misfolding is interrelated to several diseases, including neurodegenerative diseases and type II diabetes. Misfolded/unfolded proteins produce soluble oligomers that accumulate into “amyloid plaques”. Inhibition of amyloid‐plaque formation by those misfolded/unfolded proteins will lead to th...
Autores principales: | Mukherjee, Meghomukta, Jana, Jagannath, Chatterjee, Subhrangsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754551/ https://www.ncbi.nlm.nih.gov/pubmed/29318099 http://dx.doi.org/10.1002/open.201700131 |
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