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Can circulating tumor DNA be used for direct and early stage cancer detection?

In the August 16th issue of Science Translational Medicine, Phallen et al propose a method for early cancer diagnosis by using circulating tumor DNA (1). One major advance of this paper includes optimized sequencing of cell-free/circulating tumor DNA (ctDNA) without knowledge of tumor mutations. Eva...

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Detalles Bibliográficos
Autores principales: Diamandis, Eleftherios P, Fiala, Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754742/
https://www.ncbi.nlm.nih.gov/pubmed/29333251
http://dx.doi.org/10.12688/f1000research.13440.1