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Aminoglycoside interactions and impacts on the eukaryotic ribosome

Aminoglycosides are chemically diverse, broad-spectrum antibiotics that target functional centers within the bacterial ribosome to impact all four principle stages (initiation, elongation, termination, and recycling) of the translation mechanism. The propensity of aminoglycosides to induce miscoding...

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Detalles Bibliográficos
Autores principales: Prokhorova, Irina, Altman, Roger B., Djumagulov, Muminjon, Shrestha, Jaya P., Urzhumtsev, Alexandre, Ferguson, Angelica, Chang, Cheng-Wei Tom, Yusupov, Marat, Blanchard, Scott C., Yusupova, Gulnara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754804/
https://www.ncbi.nlm.nih.gov/pubmed/29208708
http://dx.doi.org/10.1073/pnas.1715501114