Cargando…
Aminoglycoside interactions and impacts on the eukaryotic ribosome
Aminoglycosides are chemically diverse, broad-spectrum antibiotics that target functional centers within the bacterial ribosome to impact all four principle stages (initiation, elongation, termination, and recycling) of the translation mechanism. The propensity of aminoglycosides to induce miscoding...
Autores principales: | Prokhorova, Irina, Altman, Roger B., Djumagulov, Muminjon, Shrestha, Jaya P., Urzhumtsev, Alexandre, Ferguson, Angelica, Chang, Cheng-Wei Tom, Yusupov, Marat, Blanchard, Scott C., Yusupova, Gulnara |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754804/ https://www.ncbi.nlm.nih.gov/pubmed/29208708 http://dx.doi.org/10.1073/pnas.1715501114 |
Ejemplares similares
-
Accuracy mechanism of eukaryotic ribosome translocation
por: Djumagulov, Muminjon, et al.
Publicado: (2021) -
Elongation factor-Tu can repetitively engage aminoacyl-tRNA within the ribosome during the proofreading stage of tRNA selection
por: Morse, Justin C., et al.
Publicado: (2020) -
Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy: A Structural Perspective
por: Pellegrino, Simone, et al.
Publicado: (2021) -
Alarmone Ap4A is elevated by aminoglycoside antibiotics and enhances their bactericidal activity
por: Ji, Xia, et al.
Publicado: (2019) -
Ribosome biochemistry in crystal structure determination
por: Yusupova, Gulnara, et al.
Publicado: (2015)