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Metagenomic deep sequencing of aqueous fluid detects intraocular lymphomas

INTRODUCTION: Currently, the detection of pathogens or mutations associated with intraocular lymphomas heavily relies on prespecified, directed PCRs. With metagenomic deep sequencing (MDS), an unbiased high-throughput sequencing approach, all pathogens as well as all mutations present in the host’s...

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Detalles Bibliográficos
Autores principales: Gonzales, John, Doan, Thuy, Shantha, Jessica G, Bloomer, Michele, Wilson, Michael R, DeRisi, Joseph L, Acharya, Nisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754869/
https://www.ncbi.nlm.nih.gov/pubmed/29122821
http://dx.doi.org/10.1136/bjophthalmol-2017-311151