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A novel variant translocation (1;9)(p22;q34) resulting in a DEK/NUP214 fusion gene in a patient with acute myeloid leukemia: A case report

The present case report describes a 46-year-old female patient diagnosed with M4 acute myeloid leukemia (AML), accompanied with a t(1;9)(p22;q34) chromosomal abnormality. Transcriptome sequencing identified a DEK proto-oncogene (DEK)/nucleoporin (NUP)214 fusion gene, which results from the t(6;9)(p2...

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Detalles Bibliográficos
Autores principales: Hao, Qishan, Zhang, Qi, Li, Chengwen, Wei, Shuning, Li, Qinghua, Song, Yang, Mi, Yingchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754883/
https://www.ncbi.nlm.nih.gov/pubmed/29344131
http://dx.doi.org/10.3892/ol.2017.7133