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Construction of the POT1 promoter report gene vector, and the effect and underlying mechanism of the POT1 promoter in regulating telomerase and telomere length

By using human genomic DNA as a template to clone protection of telomere 1 (POT1) promoter gene segments and construct the POT1 promoter luciferase report gene vector (pGL3-Control-POT1-promoter), the association between POT1, and the regulation of telomerase and telomere length was investigated. In...

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Detalles Bibliográficos
Autores principales: Zeng, Liang, Wang, Yue-Li, Wang, Fa, Cui, Shi-Quan, Hu, Liang, Huang, Di-Nan, Hou, Gan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754914/
https://www.ncbi.nlm.nih.gov/pubmed/29344158
http://dx.doi.org/10.3892/ol.2017.7127