Cargando…

UVB radiation represses CYLD expression in melanocytes

CYLD lysine 63 deubiquitinase (CYLD) was originally identified as a tumor suppressor that is mutated in familial cylindromatosis. Unlike in cylindromatosis, downregulation of the deubiquitinase CYLD in melanoma, a highly aggressive tumor, is not caused by mutations in the CYLD gene, but rather by a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuphal, Silke, Schneider, Nadja, Massoumi, Ramin, Hellerbrand, Claus, Bosserhoff, Anja Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754916/
https://www.ncbi.nlm.nih.gov/pubmed/29344161
http://dx.doi.org/10.3892/ol.2017.7120