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Renal mitochondria can withstand hypoxic/ischemic injury secondary to renal failure in uremic rats pretreated with sodium thiosulfate

BACKGROUND: Sodium thiosulfate (STS) is a potent drug used to treat calcific uremic arteriopathy in dialysis patients and its mode of action is envisaged by calcium chelation and antioxidant potential. STS's action on mitochondrial dysfunction, one of the major players in the pathology of vascu...

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Detalles Bibliográficos
Autores principales: Mohan, Dhivya, Balasubramanian, Eswari Dhivya, Ravindran, Sriram, Kurian, Gino A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754940/
https://www.ncbi.nlm.nih.gov/pubmed/29326493
http://dx.doi.org/10.4103/ijp.IJP_751_16