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Upregulation of Neural Precursor Cell Expressed Developmentally Downregulated 4-1 is Associated with Poor Prognosis and Chemoresistance in Lung Adenocarcinoma

BACKGROUND: The E3 ubiquitin ligase neural precursor cell expressed developmentally downregulated 4-1 (NEDD4-1) negatively regulates phosphatase and tensin homolog deleted on chromosome 10 (PTEN) protein levels through polyubiquitination and proteolysis, but its significance in lung cancer is still...

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Detalles Bibliográficos
Autores principales: Song, Ying-Hua, Zhang, Cai-Qing, Chen, Fang-Fang, Lin, Xiao-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754953/
https://www.ncbi.nlm.nih.gov/pubmed/29271375
http://dx.doi.org/10.4103/0366-6999.221262