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Notch1 signaling in melanoma cells promoted tumor-induced immunosuppression via upregulation of TGF-β1

BACKGROUND: The receptors of Notch family play an important role in controlling the development, differentiation, and function of multiple cell types. The aim of this study is to investigate the role of Notch1 signaling upon immune suppression induced by melanoma cells. METHODS: Melanoma cell line B...

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Detalles Bibliográficos
Autores principales: Yang, Zike, Qi, Yanxia, Lai, Nan, Zhang, Jiahe, Chen, Zehong, Liu, Mingyu, Zhang, Wan, Luo, Rongcheng, Kang, Shijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755139/
https://www.ncbi.nlm.nih.gov/pubmed/29301578
http://dx.doi.org/10.1186/s13046-017-0664-4