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MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer
BACKGROUND: Aberrant activation of the Wnt/β-catenin signaling pathway is frequently observed in colorectal cancer (CRC). β-catenin is the major Wnt signaling pathway effector and inactivation of adenomatous polyposis coli (APC) results in nuclear accumulation of β-catenin. It has been suggested tha...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755155/ https://www.ncbi.nlm.nih.gov/pubmed/29304823 http://dx.doi.org/10.1186/s12943-017-0753-1 |