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MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer

BACKGROUND: Aberrant activation of the Wnt/β-catenin signaling pathway is frequently observed in colorectal cancer (CRC). β-catenin is the major Wnt signaling pathway effector and inactivation of adenomatous polyposis coli (APC) results in nuclear accumulation of β-catenin. It has been suggested tha...

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Detalles Bibliográficos
Autores principales:	Zhang, Ying, Guo, Lu, Li, Yuhuan, Feng, Gui-Hai, Teng, Fei, Li, Wei, Zhou, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755155/ https://www.ncbi.nlm.nih.gov/pubmed/29304823 http://dx.doi.org/10.1186/s12943-017-0753-1

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